Pharmacokinetic and Pharmacodynamic (PK/PD) Modelling
From core concepts to practical application, including therapeutic proteins and monoclonal antibodies
- Expert speaker faculty
- Industry + authority perspective
- Real-world data examples
- Hands-on practical exercises
- Latest industry developments
- Officially certified: ISO 9001 + 21001
Online-Seminar
From
1.990,00 €
plus VAT
Services & Process
Veranstaltung - 1.990,-€ zzgl. MwSt.
The participation fee includes documentation for download, a certificate, access to the Learning Space and technical support including PreMeeting.
Period:
Day 1+2 from 9:00 a.m. - 5:00 p.m.
CET - Online training
You may dial in 30 minutes before the training starts
Booking details
Online-Seminar
From
1.990,00 €
plus VAT
Services & Process
Veranstaltung - 1.990,-€ zzgl. MwSt.
The participation fee includes documentation for download, a certificate, access to the Learning Space and technical support including PreMeeting.
Period:
Day 1+2 from 9:00 a.m. - 5:00 p.m.
CET - Online training
You may dial in 30 minutes before the training starts
You want to be able to discuss pharmacokinetic and pharmacodynamic modelling with your colleagues more confidently? This seminar gives you the know-how, from compartment models and preclinical-to-clinical translation to the specific characteristics of therapeutic proteins and monoclonal antibodies, combined with hands-on practical exercises.
Your speakers
What to Expect
- Core concepts of pharmacokinetic (PK) and pharmacodynamic (PD) modelling
- Translation from preclinical to clinical trials
- Practical application of PK/PD models using real data examples
- Special PK/PD aspects of therapeutic proteins and monoclonal antibodies, including drug-drug interactions
Who Should Attend
This seminar is designed for professionals in drug development who want to understand the concepts and results of PK/PD modelling, whether or not they are directly involved in the modelling work themselves, for example from clinical development, regulatory affairs, project management, or drug safety.
It is equally suited to scientists moving into a role with closer contact to PK/PD modelling and to anyone who wants to engage confidently with colleagues working in this field.
Objective of the Event
This seminar provides the foundations in pharmacokinetics and pharmacodynamics needed to follow and contribute to PK/PD modelling work, covering key parameters, compartment models, and the translation of preclinical data into the first-in-human trial.
As participant you learn assessing current developments in the field and engaging with internal PK/PD projects, whether as a contributor or as a colleague working alongside the modelling team.
Practical exercises let you apply a PK/PD model to real data yourself, building the confidence to discuss modelling approaches with colleagues in the field. The program also addresses the specific pharmacokinetic characteristics of therapeutic proteins and monoclonal antibodies, including immunogenicity and drug-drug interactions, which are increasingly relevant in current drug development.
Your Benefit
- You will be able to follow and contribute to internal PK/PD projects with a solid understanding of the underlying concepts and methods.
- You will gain the confidence to discuss modelling approaches and results with colleagues working in PK/PD modelling, on equal footing.
- You will experience through hands-on exercises, how a PK/PD model is applied to real data, giving you a practical sense of what the analysis involves.
- You will understand the specific PK/PD characteristics of therapeutic proteins and monoclonal antibodies, which are increasingly relevant across current drug development projects.
Programme
Day 1+2 from 9:00 a.m. - 5:00 p.m.
CET - Online training
Day 1
Dr. Andreas Becker
Dr Andreas Becker
- Exposure parameters
- Bioavailability
- Dose proportionality
Dr Britta Steffens, Dr Gilbert Koch
- Basic concept of compartment models
- Transport processes and elimination
- Analysis methods and software tools
Dr Elke Stahl
- Preclinical studies on pharmacology and safety
- Dose selection - starting dose for the first clinical trial
Dr Andreas Becker
- Clinical pharmacology package for the authorisation of a new active substance
- General consideration on study designs
- Examples
Welcome, introduction, expectations
Parameters of model-independent pharmacokinetics
Parameters of model-independent pharmacokinetics
Dr Andreas Becker
- Exposure parameters
- Bioavailability
- Dose proportionality
Basic knowledge of pharmacokinetics modelling
Basic knowledge of pharmacokinetics modelling
Dr Britta Steffens, Dr Gilbert Koch
- Basic concept of compartment models
- Transport processes and elimination
- Analysis methods and software tools
From the target to the first in human trial (FIH)
From the target to the first in human trial (FIH)
Dr Elke Stahl
- Preclinical studies on pharmacology and safety
- Dose selection - starting dose for the first clinical trial
Pharmacokinetic studies in drug development
Pharmacokinetic studies in drug development
Dr Andreas Becker
- Clinical pharmacology package for the authorisation of a new active substance
- General consideration on study designs
- Examples
Recap and questions
End of seminar day I
Day 2
Dr Britta Steffens, Dr Gilbert Koch
- Principles of population pharmacokinetics
- Covariate models
- Analysis strategies and good modeling practice
Dr Britta Steffens, Dr Gilbert Koch
- Saturation models, e.g. Emax models
- Linking pharmacokinetics and pharmacodynamics through response models
D. Britta Steffens, Dr Gilbert Koch, Dr Andreas Becker
Using simple tools, participants will be shown and given the opportunity to practise how to analyse data from PK/PD studies, i.e. how to apply a PK/PD model (2 examples).
Dr Niklas Czeloth
- Structure, function and pharmacokinetics of proteins
- Pharmacokinetics of monoclonal antibodies
Dr Niklas Czeloth
- The influence of immunogenicity on PK
- Dose-response and concentration-response relationships
- Suitable markers for efficacy and safety
Dr Niklas Czeloth
- Drug-drug interactions (DDI) involving therapeutic proteins
Population pharmacokinetics
Population pharmacokinetics
Dr Britta Steffens, Dr Gilbert Koch
- Principles of population pharmacokinetics
- Covariate models
- Analysis strategies and good modeling practice
Introduction to pharmacokinetics/pharmacodynamics modelling
Introduction to pharmacokinetics/pharmacodynamics modelling
Dr Britta Steffens, Dr Gilbert Koch
- Saturation models, e.g. Emax models
- Linking pharmacokinetics and pharmacodynamics through response models
Pharmacokinetics/pharmacodynamics analyses using practical examples
Pharmacokinetics/pharmacodynamics analyses using practical examples
D. Britta Steffens, Dr Gilbert Koch, Dr Andreas Becker
Using simple tools, participants will be shown and given the opportunity to practise how to analyse data from PK/PD studies, i.e. how to apply a PK/PD model (2 examples).
Special features of the pharmacokinetics of therapeutic proteins
Special features of the pharmacokinetics of therapeutic proteins
Dr Niklas Czeloth
- Structure, function and pharmacokinetics of proteins
- Pharmacokinetics of monoclonal antibodies
The relationship between pharmacokinetics and pharmacodynamics - the example of monoclonal antibodies
The relationship between pharmacokinetics and pharmacodynamics - the example of monoclonal antibodies
Dr Niklas Czeloth
- The influence of immunogenicity on PK
- Dose-response and concentration-response relationships
- Suitable markers for efficacy and safety
Therapeutic proteins and pharmacokinetic drug-drug interactions
Therapeutic proteins and pharmacokinetic drug-drug interactions
Dr Niklas Czeloth
- Drug-drug interactions (DDI) involving therapeutic proteins
Recap and questions
Downloads
Request the documents using our form.

Abbreviation List Biotech
Further Informations
In-house seminars: Advanced training tailor-made!
You are looking for this topic for several employees?
We offer the right solution at your site or in virtual format!
We also offer this seminar as an in-house seminar.
Take advantage of the proven concepts of our open seminars and bring your employees to the same level of knowledge quickly and easily.
We will be happy to send you a non-binding offer.
Modular qualification course to become "Development Experts Biologics"
This seminar is elective module of our qualification course to become a "Development Experts Biologics.
The program structure:
- You will attend our basic course "Biopharmaceuticals" (day I+II
; day III is an elective module)
- Afterward, you’ll participate in 3 additional elective seminar modules (= 3 seminar days), which you’ll select individually from the program curriculum
- You’ll receive structured professional development and comprehensive knowledge on topics related to the development and manufacture of biologics
- You can specialise by selecting seminars tailored to your specific area of focus
Benefits of a FORUM Institut training course
FORUM Institut’s all-in-one training platform uses the latest teaching methods.
All our online training courses take place in the Learning Space, our holistic learning environment with many features that promote effective and sustainable learning.
- Live and interactive learning on our Learning Space training platform
- A platform with many features: events rooms, chat, course agendas and documents, surveys, workshop rooms and much more
- Easy surveys with Slido
- ‘Deluxe’ chat: group chats, one-to-one chats, one-to-one video chats
- A central repository for documents and media
- Other services and apps such as Padlet and Mentimeter available directly on the platform
- The perfect marriage of teaching methods and technology
- High level of interactivity with plenty of opportunity for questions
- Continuous support throughout the event to ensure the most effective learning
- Free technical pre-meeting to start off your training on the right foot
Technical requirements
You need a reliable Internet connection to take part in our online events. To have the best possible learning experience, we recommend that you use the latest version of the Microsoft Edge or Google Chrome browsers. You will need a headset, loudspeaker or telephone to play the audio. Further information is available here. Please check beforehand that your microphone or headset and camera are working properly. Do not access our services from a VPN since there are issues with the audio over such connections.
We have integrated Zoom video conferencing software into our Learning Space for our online training courses. If you are not authorised to use Zoom, please get in touch with us so we can make alternative arrangements for you to take part in our online training.
Free pre-meeting and technology check
You can attend one of our pre-meetings and explore our Learning Space free of charge. Registration is not required. You can find available dates for a pre-meeting in your customer portal. Click the green ‘Participate’ button in the pre-meeting in the customer portal and you will be redirected to the Learning Space.
The pre-meeting gives you the opportunity to explore our Learning Space and to familiarise yourself with the technology to start off your online training on the right foot. This is a non-binding offer for all our customers and not a prerequisite for participation. If a pre-meeting date does not suit you but you would still like a technology check, please contact us.
Our Recommendations
Further Information
Your Contact Person
We are happy to advise you personally and individually.

Dr. Birgit Wessels
Conference Manager
+49 6221 500-652
b.wessels@forum-institut.de







